DPF3 Antibody - middle region : Biotin (ARP34293_P050-Biotin)

Product Specifications

Gene Name

D4, zinc and double PHD fingers, family 3

Gene Aliases

CERD4, BAF45C

Gene ID

8110

Swiss Prot

Q92784

Accession Number

NP_036206

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DPF3

Target

DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac) . In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.

Partner Proteins

SMARCA4; SMARCA2; RELA; NFKB1; SMARCD1; SMARCC1; SMARCB1; ESRRA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

DPF3 is supported by BioGPS gene expression data to be expressed in NCIH226

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

References & Citations

Hoyal, C.R., (er) J Carcinog 4, 13 (2005)

Shipping Conditions

Wet Ice

Protein Length

357

NCBI Gene Symbol

DPF3

NCBI GB Accession Number

DPF3

Host or Source

Rabbit

Protein Name

Zinc finger protein DPF3

Nucleotide Accession Number

NM_012074

Peptide Sequence

KDGFTSESTTLEALLRGEGVEKKVDAREEESIQEIQRVLENDENVEEGNE

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