RNF2 Antibody - middle region : Biotin (ARP34289_P050-Biotin)

Product Specifications

Gene Name

Ring finger protein 2

Gene Aliases

BAP1, DING, BAP-1, HIPI3, RING2, RING1B

Gene ID

6045

Swiss Prot

Q99496

Accession Number

NP_009143

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RNF2

Target

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2) . Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Partner Proteins

BMI1; SCMH1; HIST2H2AC; UBE2D3; AMBRA1; WASH1; BECN1; ATG14; PIK3C3; TARDBP; SNAI1; NEDD8; UBC; EIF3I; ALYREF; RBM5; RCL1; TRIM28; CEBPZ; SUGP2; G3BP1; AKAP9; YAF2; LRPPRC; KIF20A; RAD50; ARPC4; ABCB6; SMC4; ACOT8; HNRNPDL; THOC1; THRAP3; RBM8A; KIAA0020

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

RNF2 is supported by BioGPS gene expression data to be expressed in Daudi

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.