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AFF3 Antibody - middle region : FITC (ARP34237_P050-FITC)

Product Specifications

Gene Name

AF4/FMR2 family, member 3

Gene Aliases

LAF4, MLLT2-like

Gene ID

3899

Swiss Prot

P51826

Accession Number

NP_002276

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human AFF3

Target

AFF3 is a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL.This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Partner Proteins

CDK9; MLLT3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 86%; Human: 100%; Mouse: 93%; Pig: 86%; Rabbit: 77%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

133kDa

References & Citations

To, M.D., (2005) Int. J. Cancer 115 (4), 568-574

Shipping Conditions

Wet Ice

Protein Length

1226

NCBI Gene Symbol

AFF3

NCBI GB Accession Number

AFF3

Host or Source

Rabbit

Protein Name

AF4/FMR2 family member 3

Nucleotide Accession Number

NM_002285

Peptide Sequence

APATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKSQGEKD

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