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AFDN Antibody - N-terminal region : HRP (ARP34225_T100-HRP)

Product Specifications

Gene Name

Afadin, adherens junction formation factor

Gene Aliases

AF6, MLLT4, MLL-AF6, l-afadin

Gene ID

4301

Swiss Prot

P55196

Accession Number

EAW47480

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT4

Target

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t (6;11) (q27; q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.

Partner Proteins

UBC; LGR4; LATS2; YWHAQ; YWHAE; VCAM1; SMAD2; ITGA4; GRB2; FN1; SIRT7; HNRNPA1; ARRB2; YWHAG; YWHAB; KMT2A; MEN1; PVRL4; PICK1; RIT2; SORBS2; F11R; NRXN2; SSX2IP; RIT1; NRXN3; PVRL3; PVRL1; MRAS; SORBS1; EPHB6; EPHA7; JAG1; EPHB3; RALGDS; TJP1; EPHB2; PVR

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

MLLT4 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 85%; Rat: 100%; Yeast: 92%; Zebrafish: 91%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-AFDN (ARP34225_T100-HRP) antibody

Protein Length

674

NCBI Gene Symbol

AFDN

NCBI GB Accession Number

AFDN

Host or Source

Rabbit

Protein Name

Afadin

Nucleotide Accession Number

NM_001040000

Peptide Sequence

GVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRPFQGEDVENSRLAAE

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