RBBP5 Antibody - middle region : Biotin (ARP34206_P050-Biotin)

Product Specifications

Gene Name

Retinoblastoma binding protein 5

Gene Aliases

RBQ3, SWD1

Gene ID

5929

Swiss Prot

Q15291

Accession Number

NP_005048

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RBBP5

Target

RBBP5 contains 6 WD repeats. It binds preferentially to underphosphorylated retinoblastoma protein. The protein encoded by this gene is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1 AU099032.1 13-13 2-26 CD710496.1 39-63 27-567 BC053856.1 17-557 568-1604 BC037284.2 540-1576 1605-2978 BC053856.1 1595-2968 2979-2979 BC037284.2 2838-2838 2980-2992 AA235403.1 1-13 2993-3136 BC037284.2 2851-2994 3137-3318 BC053856.1 3125-3306 3319-3334 BC037284.2 3177-3192 3335-3342 BG392257.1 177-184 3343-3587 BC037284.2 3200-3444 3588-3683 CB133829.1 341-436

Partner Proteins

CXXC1; SETD1A; ASH2L; PPARG; KMT2A; KMT2D; SENP3; UBE2I; UBC; SUMO2; Fbxl16; KDM6B; KDM6A; SMARCD1; KLC2; SRRT; DHX38; SMARCE1; SMARCD2; HCFC1; SMARCC1; MEN1; USF1; WDR5; ELAVL1; ESR1; KANSL1; DPY30; KDM4B; KMT2B; PSMA3; CTBP1; TBK1; CDC73; HIST3H3; PYGO2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

RBBP5 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.