ASH2L Antibody - middle region : Biotin (ARP34202_P050-Biotin)

Product Specifications

Gene Name

Ash2 (absent, small, or homeotic) -like (Drosophila)

Gene Aliases

ASH2, Bre2, ASH2L1, ASH2L2

Gene ID

9070

Swiss Prot

Q9UBL3

Accession Number

NP_004665

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ASH2L

Target

ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. The protein may function as a transcriptional regulator and play a role in hematopoiesis.

Partner Proteins

CXXC1; DPY30; SETD1A; RBBP5; PPARG; KMT2A; KMT2D; UBC; SENP3; KDM6A; PPP1CC; SMAD9; KDM6B; WWP1; BRCA1; BARD1; WDR5; MEN1; USF1; KMT2C; HCFC2; SETD1B; KDM4B; KMT2B; HCFC1; ESR1; CDC73; HIST3H3; PYGO2; WDR82; PSMC5; PRMT1; E2F4; E2F1; PAGR1; NCOA6; PAXIP1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

References & Citations

LÃ¼scher-Firzlaff J, et al. Cancer Res, 2008 Feb 1. PMID 18245475

Shipping Conditions

Wet Ice

Protein Length

628

NCBI Gene Symbol

ASH2L

NCBI GB Accession Number

ASH2L

Host or Source

Rabbit

Protein Name

Set1/Ash2 histone methyltransferase complex subunit ASH2

Nucleotide Accession Number

NM_004674

Peptide Sequence

AAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFN

Subunit

ASH2

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