SMARCB1 Antibody - N-terminal region : Biotin (ARP34171_P050-Biotin)

Product Specifications

Gene Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

Gene Aliases

RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144

Gene ID

6598

Swiss Prot

Q12824

Accession Number

NP_003064

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCB1

Target

The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors.

Partner Proteins

UBC; SOX2; tat; EPAS1; TRA2A; NCSTN; SAP18; EIF4A3; ARID1A; DPF1; VTN; TOP2B; SON; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCA4; SMARCA2; SMARCC1; ARID1B; HDAC2; APP; PHF10; UBD; COPS5; CUL3; TFAP4; CAND1; RB1CC1; UBB; CEBPB; UL114; UL44; CHFR; DP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.