G22P1 Antibody - N-terminal region : Biotin (ARP34116_T100-Biotin)
Product Specifications
Gene Name
X-ray repair complementing defective repair in Chinese hamster cells 6
Gene Aliases
ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Gene ID
2547
Swiss Prot
Q6FG89
Accession Number
NP_001460
Host
Rabbit
Reactivity
Human, Cow
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human G22P1
Target
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Partner Proteins
UBC; ELF3; EHF; CHD1L; SUMO2; SUMO3; MDM2; EMD; ATRX; RPA3; RPA2; RPA1; PCNA; EED; PRPF40A; SUPT5H; ST13; SET; PLOD2; PIN1; NARS; MSH2; RPSA; JUP; IMPDH1; MSH6; GART; DPYSL3; CTNNA1; SAMHD1; ATP6V1B2; GANAB; SWAP70; WBP4; HYOU1; FARSB; RANBP3; CUL2; CSDE1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Sample Type
XRCC6 is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/ml
Homology
Cow: 79%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
70kDa
References & Citations
Sawchuk, D.J., et al., (2004) J. Biol. Chem. 279 (28), 29821-29831
Shipping Conditions
Wet Ice
Protein Length
609
NCBI Gene Symbol
XRCC6
NCBI GB Accession Number
XRCC6
Host or Source
Rabbit
Protein Name
X-ray repair cross-complementing protein 6
Nucleotide Accession Number
NM_001469
Peptide Sequence
MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFE
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