BRD8 Antibody - middle region : Biotin (ARP34090_P050-Biotin)
Product Specifications
Gene Name
Bromodomain containing 8
Gene Aliases
SMAP, p120, SMAP2
Gene ID
10902
Swiss Prot
Q9H0E9
Accession Number
NP_631938
Host
Rabbit
Reactivity
Human, Cow, Dog, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human BRD8
Target
BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator.The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.
Partner Proteins
FSD2; MIS18A; SUMO2; UBC; SUMO1; SOX2; Chek2; DMAP1; KAT5; MAX; MYC; MORF4L1; MORF4L2; MRGBP; TP63; TP73; TP53; THRB; TRRAP; PPARG; WEE1; RXRA; ING3; RB1; KDM5A; RBL2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
BRD8 is supported by BioGPS gene expression data to be expressed in HEK293T
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 92%; Horse: 92%; Human: 100%; Rabbit: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
135kDa
References & Citations
Olsen, J.V., (2006) Cell 127 (3), 635-648
Shipping Conditions
Wet Ice
Protein Length
1235
NCBI Gene Symbol
BRD8
NCBI GB Accession Number
BRD8
Host or Source
Rabbit
Protein Name
Bromodomain-containing protein 8
Nucleotide Accession Number
NM_139199
Peptide Sequence
LRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSH
Curated Selection
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