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BRD8 Antibody - middle region : Biotin (ARP34090_P050-Biotin)

Product Specifications

Gene Name

Bromodomain containing 8

Gene Aliases

SMAP, p120, SMAP2

Gene ID

10902

Swiss Prot

Q9H0E9

Accession Number

NP_631938

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human BRD8

Target

BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator.The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.

Partner Proteins

FSD2; MIS18A; SUMO2; UBC; SUMO1; SOX2; Chek2; DMAP1; KAT5; MAX; MYC; MORF4L1; MORF4L2; MRGBP; TP63; TP73; TP53; THRB; TRRAP; PPARG; WEE1; RXRA; ING3; RB1; KDM5A; RBL2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

BRD8 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Horse: 92%; Human: 100%; Rabbit: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

135kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

1235

NCBI Gene Symbol

BRD8

NCBI GB Accession Number

BRD8

Host or Source

Rabbit

Protein Name

Bromodomain-containing protein 8

Nucleotide Accession Number

NM_139199

Peptide Sequence

LRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSH

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