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BRD8 Antibody - middle region : HRP (ARP34090_P050-HRP)

Product Specifications

Gene Name

Bromodomain containing 8

Gene Aliases

SMAP, p120, SMAP2

Gene ID

10902

Swiss Prot

Q9H0E9

Accession Number

NP_631938

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human BRD8

Target

BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator.The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.

Partner Proteins

FSD2; MIS18A; SUMO2; UBC; SUMO1; SOX2; Chek2; DMAP1; KAT5; MAX; MYC; MORF4L1; MORF4L2; MRGBP; TP63; TP73; TP53; THRB; TRRAP; PPARG; WEE1; RXRA; ING3; RB1; KDM5A; RBL2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

BRD8 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Horse: 92%; Human: 100%; Rabbit: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

135kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

1235

NCBI Gene Symbol

BRD8

NCBI GB Accession Number

BRD8

Host or Source

Rabbit

Protein Name

Bromodomain-containing protein 8

Nucleotide Accession Number

NM_139199

Peptide Sequence

LRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSH

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