UBE2N Antibody - middle region: Biotin (ARP34089_T100-Biotin)
Product Specifications
Gene Name
Ubiquitin-conjugating enzyme E2N
Gene Aliases
UBC13, UbcH13, HEL-S-71, UbcH-ben, UBCHBEN; UBC13
Gene ID
7334
Swiss Prot
P61088
Accession Number
NP_003339
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human UBE2N
Target
UBE2N encodes a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
Partner Proteins
TRIM33; BFAR; MALT1; STUB1; BCL10; UBE2V2; UBC; TRAF6; ZNRF1; XIAP; SLX8; SLX5; MARCH7; TNF; UBE2N; RNF168; RNF8; PARK2; OTUB1; ARIH1; NEDD4L; MFN2; TRIM72; PELI3; RNF111; RNF11; BAG3; TRAF2; FN1; VCAM1; RNF126; RNF115; NBN; ATP6V1H; VPS33B; ZDHHC5; ACTR2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
UBE2N is strongly supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
17kDa
Shipping Conditions
Wet Ice
Protein Length
152
NCBI Gene Symbol
UBE2N
Protein Name
Ubiquitin-conjugating enzyme E2 N
Nucleotide Accession Number
NM_003348
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