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UBE2N Antibody - middle region : Biotin (ARP34089_T100-Biotin)

Selected Variant

ARP34089_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Ubiquitin-conjugating enzyme E2N

Gene Aliases

UBC13, UbcH13, HEL-S-71, UbcH-ben, UBCHBEN; UBC13

Gene ID

7334

Swiss Prot

P61088

Accession Number

NP_003339

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human UBE2N

Target

UBE2N encodes a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.

Partner Proteins

TRIM33; BFAR; MALT1; STUB1; BCL10; UBE2V2; UBC; TRAF6; ZNRF1; XIAP; SLX8; SLX5; MARCH7; TNF; UBE2N; RNF168; RNF8; PARK2; OTUB1; ARIH1; NEDD4L; MFN2; TRIM72; PELI3; RNF111; RNF11; BAG3; TRAF2; FN1; VCAM1; RNF126; RNF115; NBN; ATP6V1H; VPS33B; ZDHHC5; ACTR2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

UBE2N is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Bothos, J., et al., (2003) Oncogene 22 (46), 7101-7107

Shipping Conditions

Wet Ice

Protein Length

152

NCBI Gene Symbol

UBE2N

NCBI GB Accession Number

UBE2N

Host or Source

Rabbit

Protein Name

Ubiquitin-conjugating enzyme E2 N

Nucleotide Accession Number

NM_003348

Peptide Sequence

VDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQW

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