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SUPT5H Antibody - middle region : Biotin (ARP34064_P050-Biotin)

Product Specifications

Gene Name

Suppressor of Ty 5 homolog (S. cerevisiae)

Gene Aliases

SPT5, SPT5H, Tat-CT1

Gene ID

6829

Swiss Prot

O00267

Accession Number

NP_003160

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SUPT5H

Target

SUPT5H and its binding partner regulate transcriptional elongation by RNA polymerase II. SPT4 and SPT5 are involved in both 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) -mediated transcriptional inhibition and the activation of transcriptional elongation by the human immunodeficiency virus type 1 (HIV-1) Tat protein.

Partner Proteins

POLR2A; BRCA1; UBC; RNF2; SAMHD1; GANAB; SWAP70; PAICS; CARM1; FARSB; SEC24C; RANBP3; CSDE1; SF1; SET; PLOD2; MSH2; MSH6; GART; XRCC6; ATP6V1B2; SOX2; LMNA; CDK9; CCNT2; CCNT1; tat; NSMF; FN1; CSNK2A1; SIK1; ZNF512B; LMAN2; ZFYVE9; SNX4; SUPT4H1; POLR2C

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

121kDa

References & Citations

Ueki, N., (2007) Mol. Cell. Biol. 27 (14), 5246-5259

Shipping Conditions

Wet Ice

Protein Length

1087

NCBI Gene Symbol

SUPT5H

NCBI GB Accession Number

SUPT5H

Host or Source

Rabbit

Protein Name

Transcription elongation factor SPT5

Nucleotide Accession Number

NM_003169

Peptide Sequence

FEDQPEGIDLEVVTESTGKEREHNFQPGDNVEVCEGELINLQGKILSVDG

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