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RGS20 Antibody - N-terminal region: HRP (ARP34052_P050-HRP)

Product Specifications

Gene Name

Regulator of G-protein signaling 20

Gene Aliases

RGSZ1, ZGAP1, gz-GAP, g (z) GAP

Gene ID

8601

Swiss Prot

O76081

Accession Number

NP_003693

Host

Rabbit

Reactivity

Human, Mouse, Rat, Guinea Pig, Horse

Target

The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G (z) -alpha and G (alpha) -i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

KRTAP5-6; LCE3E; LCE2D; LCE2A; LCE1B; KLHL38; LCE4A; TBC1D16; CATSPER1; PTPMT1; KRTAP4-2; CRCT1; PVRL3; MAPKBP1; GLRX3; CREB5; PTGER3; OTX1; KRTAP5-9; INS; HSPD1; HOXA1; GNAI2; AQP1; FASLG; KIF1A; ADRB2; OSTM1; STMN2; GNAI3; GNAI1; GNAZ; UBC; GNAO1; TXLNA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 85%; Rat: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

Shipping Conditions

Wet Ice

Specificity

100% homologous to isoforms 1, 2, 4-6.

Protein Length

241

NCBI Gene Symbol

RGS20

Protein Name

Regulator of G-protein signaling 20

Nucleotide Accession Number

NM_003702

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