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RGS13 Antibody - middle region : Biotin (ARP34051_P050-Biotin)

Product Specifications

Gene Name

Regulator of G-protein signaling 13

Gene ID

6003

Swiss Prot

O14921

Accession Number

NP_658912

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RGS13

Target

The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.

Partner Proteins

GNAI2; GNA11; UBC; PRKACA; CREB1; GNAQ

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RGS13 is supported by BioGPS gene expression data to be expressed in Daudi

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 92%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Islam, T.C., et al., (2003) Leukemia 17 (9), 1880-1890

Shipping Conditions

Wet Ice

Protein Length

159

NCBI Gene Symbol

RGS13

NCBI GB Accession Number

RGS13

Host or Source

Rabbit

Protein Name

Regulator of G-protein signaling 13

Nucleotide Accession Number

NM_144766

Peptide Sequence

WSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQK

Frequently Asked Questions

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