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RGS13 Antibody - middle region : HRP (ARP34051_P050-HRP)

Selected Variant

ARP34051_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Regulator of G-protein signaling 13

Gene ID

6003

Swiss Prot

O14921

Accession Number

NP_658912

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RGS13

Target

The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.

Partner Proteins

GNAI2; GNA11; UBC; PRKACA; CREB1; GNAQ

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RGS13 is supported by BioGPS gene expression data to be expressed in Daudi

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 92%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Islam, T.C., et al., (2003) Leukemia 17 (9), 1880-1890

Shipping Conditions

Wet Ice

Protein Length

159

NCBI Gene Symbol

RGS13

NCBI GB Accession Number

RGS13

Host or Source

Rabbit

Protein Name

Regulator of G-protein signaling 13

Nucleotide Accession Number

NM_144766

Peptide Sequence

WSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQK

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