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RGS17 Antibody - C-terminal region : FITC (ARP34049_P050-FITC)

Selected Variant

ARP34049_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Regulator of G-protein signaling 17

Gene Aliases

RGSZ2, RGS-17, hRGS17

Gene ID

26575

Swiss Prot

Q9UGC6

Accession Number

NP_036551

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human RGS17

Target

This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Partner Proteins

LCE3C; LCE2A; LCE4A; TBC1D16; DHX37; NUFIP2; PTGER3; OTX1; RPL10A; SMCP; HOXA1; GNAI3; GNAI1; AQP1; ADRB2; RABEP1; RBBP8; UBC; OSTM1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23kDa

Shipping Conditions

Wet Ice

Protein Length

210

NCBI Gene Symbol

RGS17

NCBI GB Accession Number

RGS17

Host or Source

Rabbit

Protein Name

Regulator of G-protein signaling 17

Nucleotide Accession Number

NM_012419

Peptide Sequence

NRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGSSSE

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