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CBFA2T3 Antibody - N-terminal region : FITC (ARP33993_P050-FITC)

Product Specifications

Gene Name

Core-binding factor, runt domain, alpha subunit 2; translocated to, 3

Gene Aliases

ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3

Gene ID

863

Swiss Prot

O75082

Accession Number

NP_787127

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3

Target

The t (16;21) (q24; q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.

Partner Proteins

Zbtb38; Zbtb4; ZBTB33; GMEB2; SEC24A; MATN2; ZBTB47; UBC; RUNX1; TAL1; TRIM33; SIN3B; NCOR1; HDAC3; CBFA2T3; CBFA2T2; HDAC1; PRKAR2A; RUNX1T1; LDB1; TCF3; HDAC8; HDAC6; HDAC2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CBFA2T3 is supported by BioGPS gene expression data to be expressed in Jurkat, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

62kDa

References & Citations

Powell, J.A., et al., (2002) Genomics 80 (3), 303-310

Shipping Conditions

Wet Ice

Protein Length

567

NCBI Gene Symbol

CBFA2T3

NCBI GB Accession Number

CBFA2T3

Host or Source

Rabbit

Protein Name

Protein CBFA2T3

Nucleotide Accession Number

NM_175931

Peptide Sequence

QPRSTPPSMPPPPPAASQGATRPPSFTPHTLMNGSSHSPTAINGAPCTPN

Frequently Asked Questions

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