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KIF3B Antibody - C-terminal region : Biotin (ARP33908_P050-Biotin)

Product Specifications

Gene Name

Poly (ADP-ribose) polymerase 1

Gene Aliases

PARP, PPOL, ADPRT, ARTD1, ADPRT1, PARP-1, ADPRT 1, pADPRT-1

Gene ID

142

Swiss Prot

O15066

Accession Number

NP_004789

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KIF3B

Target

The protein encoded by the KIF3B gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.

Partner Proteins

PARP1; CASP7; CASP3; UBE2I; TP53; SUMO2; CHFR; BANP; HUWE1; MDM2; SUMO3; DNMT1; CHD1L; IVNS1ABP; DDB2; PARP9; UBC; Rnf146; APLF; UHRF1; RPA3; RPA2; RPA1; ERG; MAFF; POLG2; RPL35; RPL27A; RPL19; RAD23A; PHB; CETN2; CETN1; DDX39A; PDLIM7; RPL14; MAFK; MAFG

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

85kDa

References & Citations

Jimbo, T., et al., (2002) Nat. Cell Biol. 4 (4), 323-327

Shipping Conditions

Wet Ice

Protein Length

747

NCBI Gene Symbol

PARP1

NCBI GB Accession Number

PARP1

Host or Source

Rabbit

Protein Name

Kinesin-like protein KIF3B

Nucleotide Accession Number

NM_004798

Peptide Sequence

APKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSGRKSGSSSSSS

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