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PTHLH Antibody - middle region : HRP (ARP33885_T100-HRP)

Selected Variant

ARP33885_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Parathyroid hormone-like hormone

Gene Aliases

HHM, PLP, BDE2, PTHR, PTHRP

Gene ID

5744

Swiss Prot

P12272

Accession Number

NP_002811

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PTHLH

Target

PTHLH is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Partner Proteins

ELAVL1; PLK1; KPNB1; KLK3; PTH1R; IL6; CDK2; ARRB1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

20kDa

References & Citations

Chen, C., et al., (2004) J. Biol. Chem. 279 (28), 29121-29129

Shipping Conditions

Wet Ice

Protein Length

175

NCBI Gene Symbol

PTHLH

NCBI GB Accession Number

PTHLH

Host or Source

Rabbit

Protein Name

Parathyroid hormone-related protein

Nucleotide Accession Number

NM_002820

Peptide Sequence

YKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGVTGSGLEGDHLS

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