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ASGR2 Antibody - N-terminal region : Biotin (ARP33821_T100-Biotin)

Product Specifications

Gene Name

Asialoglycoprotein receptor 2

Gene Aliases

HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2

Gene ID

433

Swiss Prot

P07307

Accession Number

NP_001172

Host

Rabbit

Reactivity

Human, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2

Target

ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.

Partner Proteins

MROH5; CERS2; HES1; GLUD1; VKORC1; Sec61b; ERLEC1; OS9; SYVN1; DERL1; FBXO6; EDEM1; F8; ASGR2; ASGR1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

ASGR2 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Human: 100%; Pig: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Yik, J.H., et al., (2002) J.Biol.Chem.277 (43),40844-40852

Shipping Conditions

Wet Ice

Protein Length

311

NCBI Gene Symbol

ASGR2

NCBI GB Accession Number

ASGR2

Host or Source

Rabbit

Protein Name

Asialoglycoprotein receptor 2

Nucleotide Accession Number

NM_001181

Peptide Sequence

STLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLKHFPV

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