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C4BPB Antibody - N-terminal region : Biotin (ARP33814_P050-Biotin)

Product Specifications

Gene Name

Complement component 4 binding protein, beta

Gene Aliases

C4BP

Gene ID

725

Swiss Prot

P20851

Accession Number

NP_000707

Host

Rabbit

Reactivity

Human, Dog, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human C4BPB

Target

C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.

Partner Proteins

UBC; PROS1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

C4BPB is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Dog: 86%; Human: 100%; Pig: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Anderson, N.L., et al., (2004) Mol. Cell Proteomics 3 (4), 311-326

Shipping Conditions

Wet Ice

Protein Length

252

NCBI Gene Symbol

C4BPB

NCBI GB Accession Number

C4BPB

Host or Source

Rabbit

Protein Name

C4b-binding protein beta chain

Nucleotide Accession Number

NM_000716

Peptide Sequence

CCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLV

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