C4BPB Antibody - N-terminal region : FITC (ARP33814_P050-FITC)
Product Specifications
Gene Name
Complement component 4 binding protein, beta
Gene Aliases
C4BP
Gene ID
725
Swiss Prot
P20851
Accession Number
NP_000707
Host
Rabbit
Reactivity
Human, Dog, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human C4BPB
Target
C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.
Partner Proteins
UBC; PROS1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
C4BPB is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/ml
Homology
Dog: 86%; Human: 100%; Pig: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
References & Citations
Anderson, N.L., et al., (2004) Mol. Cell Proteomics 3 (4), 311-326
Shipping Conditions
Wet Ice
Protein Length
252
NCBI Gene Symbol
C4BPB
NCBI GB Accession Number
C4BPB
Host or Source
Rabbit
Protein Name
C4b-binding protein beta chain
Nucleotide Accession Number
NM_000716
Peptide Sequence
CCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLV
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