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PARP3 Antibody - C-terminal region : HRP (ARP33760_P050-HRP)

Selected Variant

ARP33760_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Poly (ADP-ribose) polymerase family member 3

Gene Aliases

IRT1, ARTD3, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3

Gene ID

10039

Swiss Prot

Q9Y6F1

Accession Number

NP_005476

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PARP3

Target

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly (ADP-ribosyl) transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

UBC; APP; PARP3; HIST1H1A; PARP1; HIST2H3C; MTHFD2; HIST2H2BE; RPA3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 91%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 85%; Rabbit: 100%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Augustin, A., et al., (2003) J. Cell. Sci. 116 (Pt 8), 1551-1562

Shipping Conditions

Wet Ice

Protein Length

532

NCBI Gene Symbol

PARP3

NCBI GB Accession Number

PARP3

Host or Source

Rabbit

Protein Name

Poly [ADP-ribose] polymerase 3

Nucleotide Accession Number

NM_005485

Peptide Sequence

LGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVP

Price

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