PARP2 Antibody - middle region : Biotin (ARP33758_P050-Biotin)

Product Specifications

Gene Name

Poly (ADP-ribose) polymerase 2

Gene Aliases

ARTD2, ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2

Gene ID

10038

Swiss Prot

Q9UGN5

Accession Number

NP_005475

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PARP2

Target

This gene encodes poly (ADP-ribosyl) transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

Partner Proteins

UHRF1; Npm1; TFAP4; UBC; RNF146; H3F3A; CBX5; TRIM28; CHD1L; TNP2; HSPA2; BUB3; CASP8; XRCC1; PARP1; CENPB; CENPA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IF, WB

Purification

Affinity Purified

Sample Type

PARP2 is strongly supported by BioGPS gene expression data to be expressed in Raji

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.