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TNKS Antibody - middle region : Biotin (ARP33755_P050-Biotin)

Product Specifications

Gene Name

Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Gene Aliases

TIN1, ARTD5, PARPL, TINF1, TNKS1, pART5, PARP5A, PARP-5a

Gene ID

8658

Swiss Prot

O95271

Accession Number

NP_003738

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TNKS

Target

TNKS may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. It has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length.

Partner Proteins

RNF146; RAPGEF2; TINF2; TNKS; TERF1; SH3BP2; APC; BLZF1; GMDS; UBC; DISC1; TNIK; SH3BP5; TERF2; FANCD2; BABAM1; VPS33A; FNBP1; MCL1; POT1; TNKS2; TNKS1BP1; NUMA1; LNPEP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

142kDa

References & Citations

Baynam, G., (2008) Am. J. Med. Genet. A 146A (12), 1565-1570

Shipping Conditions

Wet Ice

Protein Length

1327

NCBI Gene Symbol

TNKS

NCBI GB Accession Number

TNKS

Host or Source

Rabbit

Protein Name

Tankyrase-1

Nucleotide Accession Number

NM_003747

Peptide Sequence

VSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKE

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