CIR1 Antibody - middle region : Biotin (ARP33736_P050-Biotin)
Selected Variant
ARP33736_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Corepressor interacting with RBPJ, 1
Gene Aliases
CIR
Gene ID
9541
Swiss Prot
Q86X95
Accession Number
NP_004873
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human CIR1
Target
CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC) . CIR is also required for RBPSUH-mediated repression of transcription.
Partner Proteins
CEP76; NEK6; U2AF1; SRSF2; SRSF1; RP9; HDAC2; SAP30; SNW1; TCEA1; NCOR2; RBPJ
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
52kDa
Shipping Conditions
Wet Ice
Protein Length
450
NCBI Gene Symbol
CIR1
NCBI GB Accession Number
CIR1
Host or Source
Rabbit
Protein Name
Corepressor interacting with RBPJ 1
Nucleotide Accession Number
NM_004882
Peptide Sequence
GRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKK
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