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USP3 Antibody - middle region : Biotin (ARP33681_P050-Biotin)

Product Specifications

Gene Name

Ubiquitin specific peptidase 3

Gene Aliases

UBP, SIH003

Gene ID

9960

Swiss Prot

Q9Y6I4

Accession Number

NP_006528

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human USP3

Target

USP3 is a novel human ubiquitin-specific protease. The USP3 protein is a functional ubiquitin-specific protease in vitro, and is able to inhibit ubiquitin-dependent degradation of both an N-end Rule substrate and abnormal endogenous proteins in yeast. USP3 is also only the second known ubiquitin-specific protease capable of efficiently cleaving a ubiquitin-proline bond.

Partner Proteins

UBC; IFIH1; DDX58; TXNDC17; SH3BGRL3; TXLNG; ZFAND6; ATP6V1H; ELAVL1; TOR1AIP2; PRRC2B; NXN; RIMBP2; WDTC1; GNA13; EIF3I; EIF3H; EIF3G; EIF3F; EIF3D; EIF3C; EIF3B; EIF3A; PKLR; LRP1; GNAL; EIF4G1; CBR3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

USP3 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 93%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Nicassio, F., (2007) Curr. Biol. 17 (22), 1972-1977

Shipping Conditions

Wet Ice

Protein Length

520

NCBI Gene Symbol

USP3

NCBI GB Accession Number

USP3

Host or Source

Rabbit

Protein Name

Ubiquitin carboxyl-terminal hydrolase 3

Nucleotide Accession Number

NM_006537

Peptide Sequence

IEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCAL

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