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USP3 Antibody - middle region : FITC (ARP33681_P050-FITC)

Product Specifications

Gene Name

Ubiquitin specific peptidase 3

Gene Aliases

UBP, SIH003

Gene ID

9960

Swiss Prot

Q9Y6I4

Accession Number

NP_006528

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human USP3

Target

USP3 is a novel human ubiquitin-specific protease. The USP3 protein is a functional ubiquitin-specific protease in vitro, and is able to inhibit ubiquitin-dependent degradation of both an N-end Rule substrate and abnormal endogenous proteins in yeast. USP3 is also only the second known ubiquitin-specific protease capable of efficiently cleaving a ubiquitin-proline bond.

Partner Proteins

UBC; IFIH1; DDX58; TXNDC17; SH3BGRL3; TXLNG; ZFAND6; ATP6V1H; ELAVL1; TOR1AIP2; PRRC2B; NXN; RIMBP2; WDTC1; GNA13; EIF3I; EIF3H; EIF3G; EIF3F; EIF3D; EIF3C; EIF3B; EIF3A; PKLR; LRP1; GNAL; EIF4G1; CBR3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

USP3 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 93%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Nicassio, F., (2007) Curr. Biol. 17 (22), 1972-1977

Shipping Conditions

Wet Ice

Protein Length

520

NCBI Gene Symbol

USP3

NCBI GB Accession Number

USP3

Host or Source

Rabbit

Protein Name

Ubiquitin carboxyl-terminal hydrolase 3

Nucleotide Accession Number

NM_006537

Peptide Sequence

IEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCAL

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