USP3 Antibody - N-terminal region : Biotin (ARP33680_P050-Biotin)
Product Specifications
Gene Name
Ubiquitin specific peptidase 3
Gene Aliases
UBP, SIH003
Gene ID
9960
Swiss Prot
Q9Y6I4
Accession Number
NP_006528
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human USP3
Target
USP3 is a novel human ubiquitin-specific protease. The USP3 protein is a functional ubiquitin-specific protease in vitro, and is able to inhibit ubiquitin-dependent degradation of both an N-end Rule substrate and abnormal endogenous proteins in yeast. USP3 is also only the second known ubiquitin-specific protease capable of efficiently cleaving a ubiquitin-proline bond.
Partner Proteins
UBC; IFIH1; DDX58; TXNDC17; SH3BGRL3; TXLNG; ZFAND6; ATP6V1H; ELAVL1; TOR1AIP2; PRRC2B; NXN; RIMBP2; WDTC1; GNA13; EIF3I; EIF3H; EIF3G; EIF3F; EIF3D; EIF3C; EIF3B; EIF3A; PKLR; LRP1; GNAL; EIF4G1; CBR3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
USP3 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 85%; Rabbit: 92%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
59kDa
References & Citations
Puente, X.S., et al., (2003) Nat. Rev. Genet. 4 (7), 544-558
Shipping Conditions
Wet Ice
Protein Length
520
NCBI Gene Symbol
USP3
NCBI GB Accession Number
USP3
Host or Source
Rabbit
Protein Name
Ubiquitin carboxyl-terminal hydrolase 3
Nucleotide Accession Number
NM_006537
Peptide Sequence
GRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCD
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