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NR1I3 Antibody - C-terminal region : Biotin (ARP33674_T100-Biotin)

Selected Variant

ARP33674_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Nuclear receptor subfamily 1, group I, member 3

Gene Aliases

CAR, CAR1, MB67

Gene ID

9970

Swiss Prot

Q5VTW5

Accession Number

NP_005113

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NR1I3

Target

NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.

Partner Proteins

HSP90AA1; RXRA; CHD9; SNX13; SNRPD3; IGH; PSMC5; PSMC4; EIF3I; SRC; MAP4; FTH1; HNF4A; NR0B2; PPARGC1A; MED1; NCOA1; POU1F1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 77%; Dog: 77%; Guinea Pig: 85%; Horse: 75%; Human: 100%; Mouse: 92%; Pig: 92%; Rabbit: 92%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

References & Citations

Ferguson, S.S., (2005) Mol. Pharmacol. 68 (3), 747-757

Shipping Conditions

Wet Ice

Protein Length

348

NCBI Gene Symbol

NR1I3

NCBI GB Accession Number

NR1I3

Host or Source

Rabbit

Protein Name

Nuclear receptor subfamily 1 group I member 3

Nucleotide Accession Number

NM_005122

Peptide Sequence

FHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQS

Price

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