Bmi1 Antibody - middle region : HRP (ARP33655_P050-HRP)
Selected Variant
ARP33655_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Bmi1 polycomb ring finger oncogene
Gene Aliases
Bmi, Bmi-, Pcgf, Bmi-1, Pcgf4, AW546694
Gene ID
12151
Swiss Prot
P25916
Accession Number
NP_031578
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Partner Proteins
Rnf2; Eed; Aurkb; Phc2; RING1; Gata6; Mph1; Cbfb; Runx1; Cdkn2a; HIST2H2AC; Slc11a1; Dnmt3b; Kdm2b; Phc1; Cbx2; Phc3; Dmap1; CBX8; SCMH1; CBX4; SMARCA5; HSPA4
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 77%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
37kDa
Shipping Conditions
Wet Ice
Protein Length
324
NCBI Gene Symbol
BMI1
NCBI GB Accession Number
Bmi1
Host or Source
Rabbit
Protein Name
Polycomb complex protein BMI-1
Nucleotide Accession Number
NM_007552
Peptide Sequence
MDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCK
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