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LHX3 Antibody - middle region : Biotin (ARP33644_P050-Biotin)

Product Specifications

Gene Name

LIM homeobox 3

Gene Aliases

LIM3, CPHD3, M2-LHX3

Gene ID

8022

Swiss Prot

Q9UBR4-2

Accession Number

NP_055379

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human LHX3

Target

LHX3 encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. This gene encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

ISL2; IFT172; LDB1; CITED2; ISL1; RLIM; LMX1A; LHX1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Pfaeffle, R.W., (2007) J. Clin. Endocrinol. Metab. 92 (5), 1909-1919

Shipping Conditions

Wet Ice

Protein Length

402

NCBI Gene Symbol

LHX3

NCBI GB Accession Number

LHX3

Host or Source

Rabbit

Protein Name

LIM/homeobox protein Lhx3

Nucleotide Accession Number

NM_014564

Peptide Sequence

RLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVR

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