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SNIP1 Antibody - C-terminal region : Biotin (ARP33584_P050-Biotin)

Selected Variant

ARP33584_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Smad nuclear interacting protein 1

Gene Aliases

PML1, PMRED

Gene ID

79753

Swiss Prot

Q8TAD8

Accession Number

NP_078976

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human SNIP1

Target

This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED) .

Partner Proteins

CLK2; TNIP1; SUMO1; SUMO2; TTC14; PRPF40A; C17orf85; ZCCHC10; SRRM2; SF3B1; SNW1; CHERP; PRPF3; UBC; SRPK2; MFAP1; IK; CDK6; MYC; MAX; ATR; RELA; GMEB1; PIAS1; ZCCHC7; TOPORS; ZNF451; ZMYM5; UBE2I; PIAS2; PIAS4; SP100; SETDB1; HIPK1; FAF1; HIPK3; EIF3C; E

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

Shipping Conditions

Wet Ice

Protein Length

396

NCBI Gene Symbol

SNIP1

NCBI GB Accession Number

SNIP1

Host or Source

Rabbit

Protein Name

Smad nuclear-interacting protein 1

Peptide Sequence

GNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSEIDRKD

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