SF1 Antibody - middle region : FITC (ARP33493_P050-FITC)

Product Specifications

Gene Name

Splicing factor 1

Gene Aliases

BBP, MBBP, ZFM1, ZNF162, D11S636, ZCCHC25

Gene ID

7536

Swiss Prot

Q15637

Accession Number

NP_004621

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SF1

Target

SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.

Partner Proteins

KRTAP26-1; TRIM69; FAM168A; CIAO1; MKRN3; PSMA3; FUS; UBC; NEDD8; SUZ12; EED; RPL24; PLOD2; OSBP; NARS; GFPT1; GART; EIF4B; APBB1; SUPT5H; TROVE2; ITCH; PRPF40A; SAMHD1; XPO7; WBP4; FAF1; TCERG1; HSPH1; FARSB; GAS7; RANBP3; HIRIP3; HIST1H4A; XRCC5; U2AF2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

SF1 is supported by BioGPS gene expression data to be expressed in COLO205

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.