SF1 Antibody - N-terminal region : Biotin (ARP33492_P050-Biotin)
Product Specifications
Gene Name
Splicing factor 1
Gene Aliases
BBP, MBBP, ZFM1, ZNF162, D11S636, ZCCHC25
Gene ID
7536
Swiss Prot
Q15637
Accession Number
NP_004621
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SF1
Target
SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.
Partner Proteins
KRTAP26-1; TRIM69; FAM168A; CIAO1; MKRN3; PSMA3; FUS; UBC; NEDD8; SUZ12; EED; RPL24; PLOD2; OSBP; NARS; GFPT1; GART; EIF4B; APBB1; SUPT5H; TROVE2; ITCH; PRPF40A; SAMHD1; XPO7; WBP4; FAF1; TCERG1; HSPH1; FARSB; GAS7; RANBP3; HIRIP3; HIST1H4A; XRCC5; U2AF2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
SF1 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Goat: 90%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68kDa
Shipping Conditions
Wet Ice
Protein Length
639
NCBI Gene Symbol
SF1
NCBI GB Accession Number
SF1
Host or Source
Rabbit
Protein Name
Splicing factor 1
Nucleotide Accession Number
NM_004630
Peptide Sequence
LRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLIT
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