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SF1 Antibody - N-terminal region : HRP (ARP33492_P050-HRP)

Selected Variant

ARP33492_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Splicing factor 1

Gene Aliases

BBP, MBBP, ZFM1, ZNF162, D11S636, ZCCHC25

Gene ID

7536

Swiss Prot

Q15637

Accession Number

NP_004621

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SF1

Target

SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.

Partner Proteins

KRTAP26-1; TRIM69; FAM168A; CIAO1; MKRN3; PSMA3; FUS; UBC; NEDD8; SUZ12; EED; RPL24; PLOD2; OSBP; NARS; GFPT1; GART; EIF4B; APBB1; SUPT5H; TROVE2; ITCH; PRPF40A; SAMHD1; XPO7; WBP4; FAF1; TCERG1; HSPH1; FARSB; GAS7; RANBP3; HIRIP3; HIST1H4A; XRCC5; U2AF2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SF1 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 90%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

68kDa

Shipping Conditions

Wet Ice

Protein Length

639

NCBI Gene Symbol

SF1

NCBI GB Accession Number

SF1

Host or Source

Rabbit

Protein Name

Splicing factor 1

Nucleotide Accession Number

NM_004630

Peptide Sequence

LRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLIT

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