What sizes are available for NSD2 Antibody - N-terminal region : HRP (ARP33489_P050-HRP)?

NSD2 Antibody - N-terminal region : HRP (ARP33489_P050-HRP) is available in the following size(s): 100 µL.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

NSD2 Antibody - N-terminal region : HRP (ARP33489_P050-HRP)

Q: What is the catalog number for NSD2 Antibody - N-terminal region : HRP (ARP33489_P050-HRP)?

The catalog number for NSD2 Antibody - N-terminal region : HRP (ARP33489_P050-HRP) is ARP33489_P050-HRP.

Selected Variant

ARP33489_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Nuclear receptor binding SET domain protein 2

Gene Aliases

WHS, TRX5, KMT3F, KMT3G, MMSET, WHSC1, REIIBP

Gene ID

7468

Swiss Prot

O96031

Accession Number

NP_055734

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human WHSC1

Target

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t (4;14) (p16.3; q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Partner Proteins

HIST1H3A; HIST3H3; HDAC1; TRIM28; UBC; SF3A1; HNRNPR; MPHOSPH10; RAD50; SART3; NUP93; GTF3C4; NOLC1; DDX21; BAZ1B; DDX18; KHSRP; RRP1; SMARCA5; SMC1A; RBM10; XRCC5; VIM; EZR; TOP2B; TOP1; TMPO; SMARCA4; SFPQ; RPN1; RBBP4; RANGAP1; PTBP1; PRKDC; PLRG1; PKP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that WHSC1 is expressed in HepG2

Concentration

0.5 mg/ml

Homology

Dog: 93%; Guinea Pig: 88%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 76%; Rat: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

References & Citations

Santra, M., et al., (2003) Blood 101 (6), 2374-2376

Shipping Conditions

Wet Ice

Protein Length

802

NCBI Gene Symbol

NSD2

NCBI GB Accession Number

NSD2

Host or Source

Rabbit

Protein Name

Histone-lysine N-methyltransferase NSD2

Nucleotide Accession Number

NM_014919

Peptide Sequence

KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFG

Price

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