TUB Antibody - N-terminal region : Biotin (ARP33467_P050-Biotin)
Product Specifications
Gene Name
Tubby homolog (mouse)
Gene Aliases
Rd5, RDOB
Gene ID
7275
Swiss Prot
P50607
Accession Number
NP_003311
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TUB
Target
TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Partner Proteins
UBC; SUV420H2; GNAQ; SRC; ABL1; PLCG1; PIK3R1; LCK; JAK2; IRS1; GRB2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 92%; Guinea Pig: 85%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
62kDa
References & Citations
Snieder, H., (2008) Diabetologia 51 (1), 54-61
Shipping Conditions
Wet Ice
Protein Length
561
NCBI Gene Symbol
TUB
NCBI GB Accession Number
TUB
Host or Source
Rabbit
Protein Name
Tubby protein homolog
Nucleotide Accession Number
NM_003320
Peptide Sequence
DSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHKGTSGPA
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