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TP73 Antibody - middle region : Biotin (ARP33458_P050-Biotin)

Product Specifications

Gene Name

Tumor protein p73

Gene Aliases

P73

Gene ID

7161

Swiss Prot

O15350

Accession Number

NP_005418

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TP73

Target

TP73 belongs to the p53 family. It participates in the apoptotic response to DNA damage. When overproduced, it activates transcription from p53-responsive promoters and induces apoptosis. TP53 may be a tumor suppressor protein.

Partner Proteins

FUS; YAP1; WWOX; UBC; TRIM32; SOX2; PFDN5; MYC; EP300; CDK2; CCNE1; CCNB1; CCNA2; CCND1; XPO1; PIN1; AURKA; PRKACA; MAD2L1; HSPA9; CDC20; TP53BP1; RBX1; DDB1; RCHY1; KAT2B; NEDD8; MDM2; IKBKB; DAXX; CHUK; BUB1B; BRCA1; TNK2; AMPH; CREBBP; KAT5; CEP131; MD

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

References & Citations

Wei, J., (2008) Gastroenterology 134 (5), 1412-1423

Shipping Conditions

Wet Ice

Protein Length

636

NCBI Gene Symbol

TP73

NCBI GB Accession Number

TP73

Host or Source

Rabbit

Protein Name

Tumor protein p73

Nucleotide Accession Number

NM_005427

Peptide Sequence

RRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPA

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