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TCEA1 Antibody - N-terminal region : HRP (ARP33407_P050-HRP)

Selected Variant

ARP33407_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Transcription elongation factor A (SII), 1

Gene Aliases

SII, TCEA, TF2S, GTF2S, TFIIS

Gene ID

6917

Swiss Prot

P23193

Accession Number

NP_006747

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TCEA1

Target

TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.

Partner Proteins

UBC; SORD; PGD; LDHA; CSE1L; BCCIP; CHORDC1; TBP; MCM5; MCM3; MCM2; GTF2H1; GTF2F1; GTF2E1; GTF2B; CDK8; MED26; POLR2C; NAA16; RBM25; SF3B2; UBAC1; POLR2A; APP; PAF1; UBR5; CDK9; LEO1; WDR61; CDC73; RTF1; CTR9; POLR2B; DDX5; INTS1; SF3B3; SNRNP200; SF3A1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 79%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Kimura, K., (2006) Genome Res. 16 (1), 55-65

Shipping Conditions

Wet Ice

Protein Length

301

NCBI Gene Symbol

TCEA1

NCBI GB Accession Number

TCEA1

Host or Source

Rabbit

Protein Name

Transcription elongation factor A protein 1

Nucleotide Accession Number

NM_006756

Peptide Sequence

KSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDET

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