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TBX5 Antibody - N-terminal region : FITC (ARP33403_T100-FITC)

Selected Variant

ARP33403_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

T-box 5

Gene Aliases

HOS

Gene ID

6910

Swiss Prot

Q99593

Accession Number

NP_542448

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TBX5

Target

TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Partner Proteins

KDM6A; SMARCA4; KAT5; GATA4; NKX2-5

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53kDa

References & Citations

Riazi, A.M., et al., (2005) J. Biol. Chem. 280 (11), 10716-10720

Shipping Conditions

Wet Ice

Protein Length

468

NCBI Gene Symbol

TBX5

NCBI GB Accession Number

TBX5

Host or Source

Rabbit

Protein Name

T-box transcription factor TBX5

Nucleotide Accession Number

NM_080717

Peptide Sequence

NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKIT

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