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TBX5 Antibody - middle region : Biotin (ARP33402_P050-Biotin)

Product Specifications

Gene Name

T-box 5

Gene Aliases

HOS

Gene ID

6910

Swiss Prot

Q99593-2

Accession Number

NP_542449

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TBX5

Target

TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs.

Partner Proteins

KDM6A; SMARCA4; KAT5; GATA4; NKX2-5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Zaragoza, M.V., et al., () Gene 330, 38613 2004

Shipping Conditions

Wet Ice

Protein Length

349

NCBI Gene Symbol

TBX5

NCBI GB Accession Number

TBX5

Host or Source

Rabbit

Protein Name

T-box transcription factor TBX5

Nucleotide Accession Number

NM_080718

Peptide Sequence

RMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVS

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