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TBX2 Antibody - middle region : Biotin (ARP33400_P050-Biotin)

Product Specifications

Gene Name

T-box 2

Gene Aliases

VETD

Gene ID

6909

Swiss Prot

Q13207

Accession Number

NP_005985

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TBX2

Target

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX2 is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

SOX2; SUMO1; EGR1; LZTR1; CEBPE; NKX2-5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 85%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 77%; Pig: 92%; Rabbit: 92%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

References & Citations

Abrahams, A., (2008) J. Biol. Chem. 283 (4), 2223-2230

Shipping Conditions

Wet Ice

Protein Length

702

NCBI Gene Symbol

TBX2

NCBI GB Accession Number

TBX2

Host or Source

Rabbit

Protein Name

T-box transcription factor TBX2

Nucleotide Accession Number

NM_005994

Peptide Sequence

AEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDE

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