SUPT5H Antibody - C-terminal region : HRP (ARP33386_P050-HRP)
Product Specifications
Gene Name
Suppressor of Ty 5 homolog (S. cerevisiae)
Gene Aliases
SPT5, SPT5H, Tat-CT1
Gene ID
6829
Swiss Prot
O00267
Accession Number
NP_003160
Host
Rabbit
Reactivity
Human, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human SUPT5H
Target
SUPT5H and its binding partner regulate transcriptional elongation by RNA polymerase II. SPT4 and SPT5 are involved in both 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) -mediated transcriptional inhibition and the activation of transcriptional elongation by the human immunodeficiency virus type 1 (HIV-1) Tat protein.
Partner Proteins
POLR2A; BRCA1; UBC; RNF2; SAMHD1; GANAB; SWAP70; PAICS; CARM1; FARSB; SEC24C; RANBP3; CSDE1; SF1; SET; PLOD2; MSH2; MSH6; GART; XRCC6; ATP6V1B2; SOX2; LMNA; CDK9; CCNT2; CCNT1; tat; NSMF; FN1; CSNK2A1; SIK1; ZNF512B; LMAN2; ZFYVE9; SNX4; SUPT4H1; POLR2C
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 100%; Zebrafish: 92%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
121kDa
References & Citations
Bourgeois, C.F., et al., (2002) Mol. Cell. Biol. 22 (4), 1079-1093
Shipping Conditions
Wet Ice
Protein Length
1087
NCBI Gene Symbol
SUPT5H
NCBI GB Accession Number
SUPT5H
Host or Source
Rabbit
Protein Name
Transcription elongation factor SPT5
Nucleotide Accession Number
NM_003169
Peptide Sequence
PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQA
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