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STAT4 Antibody - N-terminal region : HRP (ARP33376_T100-HRP)

Product Specifications

Gene Name

Signal transducer and activator of transcription 4

Gene Aliases

SLEB11

Gene ID

6775

Swiss Prot

Q14765

Accession Number

NP_003142

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human STAT4

Target

STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

Partner Proteins

UBC; ADRB2; TRIM28; FHL1; ZNF467; PIAS2; NMI; IL12RB2; IL12RB1; MAP2K6; STAT4; MAPK14; CREBBP; JUN; STAT3; IFNGR1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

STAT4 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Dog: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

86kDa

References & Citations

Torpey, N., et al., (2004) J. Biol. Chem. 279 (25), 26789-26796

Shipping Conditions

Wet Ice

Protein Length

748

NCBI Gene Symbol

STAT4

NCBI GB Accession Number

STAT4

Host or Source

Rabbit

Protein Name

Signal transducer and activator of transcription 4

Nucleotide Accession Number

NM_003151

Peptide Sequence

IGGPLHNGLDQLQNCFTLLAESLFQLRRQLEKLEEQSTKMTYEGDPIPMQ

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