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FLJ11730 Antibody - N-terminal region : Biotin (ARP33354_P050-Biotin)

Selected Variant

ARP33354_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

MYST/Esa1-associated factor 6

Gene Aliases

EAF6, CENP-28, C1orf149, NY-SAR-91

Gene ID

64769

Swiss Prot

Q86WE3

Accession Number

NP_073593

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FLJ11730

Target

The screening of cDNA expression libraries from human tumors with serum antibody (SEREX) has proven to be a powerful method for identifying the repertoire of tumor antigens recognized by the immune system of cancer patients, referred to as the cancer immunome. In this regard, cancer/testis (CT) antigens are of particular interest because of their immunogenicity and restricted expression patterns. Synoivial sarcomas are striking with regard to CT antigen expression, however, highly expressed in sarcoma, CT antigens do not induce frequent humoral immune responses in sarcoma patients. Sera from two patients were used to immunoscreen cDNA libraries from two synovial sarcoma cell lines and normal testis, resulting in the identification of 113 distinct antigens. Sarcoma antigen NY-SAR-91 is one of them.

Partner Proteins

PLEKHF2; TRIM54; LDOC1; UBC; FXR2; H2AFZ; ELAVL1; SUMO2; JADE1; KAT5; tat; MRGBP; ING5; KAT6A; BRPF1; CCDC85B; L3MBTL2; ING3; ING4; KAT7

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

MEAF6 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23kDa

References & Citations

Lee, S.Y., et al., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2651-2656

Shipping Conditions

Wet Ice

Protein Length

201

NCBI Gene Symbol

MEAF6

NCBI GB Accession Number

MEAF6

Host or Source

Rabbit

Protein Name

Chromatin modification-related protein MEAF6

Nucleotide Accession Number

NM_022756

Peptide Sequence

HNKAAPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQM

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