C20ORF20 Antibody - middle region : Biotin (ARP33352_P050-Biotin)
Product Specifications
Gene Name
Chromosome 20 open reading frame 20
Gene Aliases
Eaf7, URCC4, MRG15BP, C20orf20
Gene ID
55257
Swiss Prot
Q9NV56
Accession Number
NP_060740
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human C20ORF20
Target
C20orf20 belongs to the EAF7 family. It is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Partner Proteins
MORF4L1; MORF4L2; NOTCH2NL; KRTAP10-7; H2AFZ; ELAVL1; SH3BP4; VAV2; UBC; H2AFV; MRFAP1; EPC1; DMAP1; MRGBP; MBTD1; EPC2; SIN3B; BRD8; RUVBL2; SRCAP; KAT5; RUVBL1; HIST2H2BE; TUBA1A; TUBB2A; RBBP7; HNRNPM; LMNA; KPNA2; KPNB1; HSPA4; HNRNPU; HNRNPK; ACTL6A
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
22kDa
References & Citations
Cai, Y., (2003) J. Biol. Chem. 278 (44), 42733-42736
Shipping Conditions
Wet Ice
Protein Length
204
NCBI Gene Symbol
MRGBP
NCBI GB Accession Number
MRGBP
Host or Source
Rabbit
Protein Name
MRG-binding protein
Nucleotide Accession Number
NM_018270
Peptide Sequence
LSTMYDMQALHESEILPFPNPERNFVLPEEIIQEVREGKVMIEEEMKEEM
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