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C20ORF20 Antibody - middle region : HRP (ARP33352_P050-HRP)

Selected Variant

ARP33352_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Chromosome 20 open reading frame 20

Gene Aliases

Eaf7, URCC4, MRG15BP, C20orf20

Gene ID

55257

Swiss Prot

Q9NV56

Accession Number

NP_060740

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human C20ORF20

Target

C20orf20 belongs to the EAF7 family. It is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Partner Proteins

MORF4L1; MORF4L2; NOTCH2NL; KRTAP10-7; H2AFZ; ELAVL1; SH3BP4; VAV2; UBC; H2AFV; MRFAP1; EPC1; DMAP1; MRGBP; MBTD1; EPC2; SIN3B; BRD8; RUVBL2; SRCAP; KAT5; RUVBL1; HIST2H2BE; TUBA1A; TUBB2A; RBBP7; HNRNPM; LMNA; KPNA2; KPNB1; HSPA4; HNRNPU; HNRNPK; ACTL6A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

22kDa

References & Citations

Cai, Y., (2003) J. Biol. Chem. 278 (44), 42733-42736

Shipping Conditions

Wet Ice

Protein Length

204

NCBI Gene Symbol

MRGBP

NCBI GB Accession Number

MRGBP

Host or Source

Rabbit

Protein Name

MRG-binding protein

Nucleotide Accession Number

NM_018270

Peptide Sequence

LSTMYDMQALHESEILPFPNPERNFVLPEEIIQEVREGKVMIEEEMKEEM

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