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HTATIP Antibody - middle region : Biotin (ARP33345_P050-Biotin)

Product Specifications

Gene Name

K (lysine) acetyltransferase 5

Gene Aliases

TIP, ESA1, PLIP, TIP60, cPLA2, HTATIP, ZC2HC5, HTATIP1, NEDFASB

Gene ID

10524

Swiss Prot

Q92993

Accession Number

NP_006379

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HTATIP

Target

HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Partner Proteins

SOX5; SIRT1; MTUS2; NINL; IKZF3; TMCC2; ESR1; PHC2; TRIM23; APBB1; STX11; ZBTB14; TUFT1; TRIM27; ODC1; TRIM37; MEOX2; MDFI; HDAC1; GOLGA2; ZBTB8A; KRTAP10-3; KRTAP10-9; PIH1D3; ZNF513; KRT40; SSX2IP; LONRF1; LZTS2; HMBOX1; CCDC136; GMCL1P1; GMCL1; ZBTB7B

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 93%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Hejna, J., (2008) J. Biol. Chem. 283 (15), 9844-9851

Shipping Conditions

Wet Ice

Protein Length

513

NCBI Gene Symbol

KAT5

NCBI GB Accession Number

KAT5

Host or Source

Rabbit

Protein Name

Histone acetyltransferase KAT5

Nucleotide Accession Number

NM_006388

Peptide Sequence

VEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEI

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