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SMARCC1 Antibody - C-terminal region : FITC (ARP33307_T100-FITC)

Product Specifications

Gene Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

Gene Aliases

Rsc8, SRG3, SWI3, BAF155, CRACC1

Gene ID

6599

Swiss Prot

Q92922

Accession Number

NP_003065

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SMARCC1

Target

SMARCC1 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.

Partner Proteins

PLSCR1; OTX1; ADAMTSL4; BAZ1B; UBC; AURKB; WWOX; EED; RNF2; BMI1; ITCH; NEDD4; HDAC6; UL29; Dlg4; tat; EPAS1; VCP; NOTCH1; ARID1B; PHF10; KDM1A; SMARCA5; ARID1A; TOP2B; SMARCE1; SMARCD2; SMARCD1; SMARCC2; SMARCB1; SMARCA4; SMARCA2; SMARCA1; RBBP5; HDAC1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Sample Type

SMARCC1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 79%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

123kDa

References & Citations

Phelan, M.L., et al., (1999) Mol. Cell 3 (2), 247-253

Shipping Conditions

Wet Ice

Protein Length

1105

NCBI Gene Symbol

SMARCC1

NCBI GB Accession Number

SMARCC1

Host or Source

Rabbit

Protein Name

SWI/SNF complex subunit SMARCC1

Nucleotide Accession Number

NM_003074

Peptide Sequence

TKSEEKETEENKELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASA

Subunit

SMARCC1

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